CD Formulation offers direct compression excipients, and we have pharmacy-related researchers and laboratory staff, as well as professional laboratory equipment, to provide product purity and properties to meet your requirements. In addition to bringing you products, we also provide customized direct compression excipients and product solutions to help you solve the problems encountered in the drug development process.
Direct tablet refers to the dry ingredients are fully mixed and pressed into tablets. This eliminates the drying step associated with wet granulation methods. It also reduces the higher costs involved in wet pelleting, including increased equipment, labor, time, process validation and energy consumption. Direct compression requires the use of excipients with strictly defined properties.
The types of direct tablet pressing agents are divided into the following parts:
1. Elastic Excipients
Elastic excipients are excipients that are deformed after being stressed and then restored to their original state after being relieved, such as starch based direct compression excipients (also viscous).
2. Plastic Excipients
Plastic excipients are particles of matter that are deformed after being compressed by force but do not recover elasticity after the force is removed. These materials include microcrystalline cellulose, etc.
3. Fragile Excipients
Fragile excipient refers to the material particles that become smaller after strong compression, such as lactose and dicalcium phosphate.
Different excipients have different compressibility and range of use, and different sensitivity to magnesium stearate due to their different properties. If the sensitivity is strong, the softening effect of the membrane is obvious.
Direct compression premixed auxiliary material, which means that a single preparation agent is mixed together to have better properties than a single preparation agent, includes the following:
CD Formulation is a leading manufacturer of excipients that help improve the performance of pharmaceuticals and other products in the pharmaceutical industry. We develop, manufacture and market pharmaceutical excipients in solid, semi-solid and liquid dosage forms. If you have any requirements on excipients, please do not hesitate to contact us by phone or email in time, our colleagues will reply to you within 2-4 working days.