Oral thin films are a very thin polymer films, consisting of a single or multi-layer polymer matrix, which are usually applied in the mouth to function. Oral thin films are usually water-based soluble polymers designed for rapid and systematic delivery of drugs, with the active substance transported directly into the bloodstream. This avoids exposing the drug to the harsh conditions of the stomach and allows this drug delivery system to deliver a greater percentage of the active compound per dose. Oral thin films technology enables rapid release of the active substance in the form of a single or multi-layer system.
Depending on the drug candidate and the targeted indication, oral thin films can be formulated as a transmucosal, in which the active substance enters the body circulation directly through the buccal mucosa, avoiding a once-through effect in the liver.
CD Formulation provides oral thin films technology services, including oral thin films formulation development, oral thin films performance testing, and process optimization services.
CD Formulation's formulation development includes the examination of film size and thickness, drug/polymer ratio, viscosity, flexibility and tensile strength, etc., and then customization according to the physicochemical properties of the drug itself, the amount of drug required and the type of oral thin films release needed, providing multi-faceted, personalized and integrated services.
CD Formulation performs characterization of the mechanical and performance properties of the films. The mechanical properties include elongation at break, folding resistance and tear resistance. The performance properties include oralthin films uniformity, impurities, and disintegration/dissolution rates.
Development of new particle engineering technologies to improve drug solubility.
Our professional pharmacy experts and laboratory instrumentation can bring you comprehensive technical services and solutions to help you achieve drug development to drug delivery integration.
CD Formulation provides integrated innovation solutions from strategy to implementation to help you increase opportunities and address challenges. Through our in-depth experience in many different industries, including consumer and technology, we bring innovative solutions and cross-industry best practices to drug development. If you have a requirement about our oral thin films services, please contact us by phone or email, our colleagues will reply to you within three working days.