Toxicological Evaluation of Cosmetics

Each country has its own regulations for cosmetic safety management, of which toxicological safety evaluation is an indispensable part. Chemicals in cosmetics may cause skin sensitization, irritation, and other hazards, and only a few tests of health chemical and microbiological indicators are not comprehensive for cosmetic safety identification. Toxicological evaluation of safety applies prescribed toxicological procedures and methods to detect and evaluate the toxicity and potential health hazards of a chemical substance through toxicological animal testing and observation of exposed people, to make a decision on whether the substance can be placed on the market, and to evaluate the safety of human use of the substance.

Toxicological Evaluation of Cosmetics

Our Services

Test scope

Raw materials, end products (general category: skin care, color cosmetics, nail and aromatic products; special category: hair care, hair coloring, perm, hair removal, breast beauty, bodybuilding, deodorant, spot and sunscreen products, etc.)

Test items

NO. Test Types NO. Test Types
1 Acute transdermal toxicity test 9 In vitro mammalian cell chromosome aberration test
2 Acute oral toxicity test 10 In vitro mammalian cell gene mutation test
3 Skin irritation/corrosiveness test 11 Mammalian bone marrow cell chromosome aberration test
4 Acute eye irritation/corrosiveness test 12 In vivo mammalian cell micronucleus test
5 Skin metaplasia test 13 Testicular germ cell chromosomal aberration test
6 Skin phototoxicity test 14 Subchronic oral toxicity test
7 Salmonella typhimurium / revert mutation test 15 Subchronic transdermal toxicity test
8 Teratogenicity test 16 Chronic toxicity/carcinogenicity combination test

Toxic metabolism and kinetic tests according to the characteristics and use of raw materials, but also consider other necessary tests. If the new raw material and has been used in cosmetics, the chemical structure and characteristics of similar raw materials, you can consider reducing some tests, the future may be based on specific requirements for specific conditions.

Experimental instruments

Liquid mass spectrometer, GC-MS, GC, LC-MS, LC, ICP-MS, atomic absorption spectrometer, atomic fluorescence spectrometer, Fourier transform infrared (FT-IR) spectroscopy, UV-Vis spectrometer, biochemical instrument, enzyme marker and other large equipment.

Our Advantages

  • Complete qualification and high guarantee

CD Formulation is qualified as an inspection and testing organization, and constructs and manages R&D laboratories, instrument laboratories and other professional laboratories in strict accordance with ISO17025 system.

  • Advanced instruments with short cycle time

The laboratory has a large number of precision testing instruments and various types of professional analytical equipment to meet customer testing of drug quality, instruments and equipment to achieve management of experimental data, real-time audit tracing, and traceability of data results, etc., to ensure the accuracy of test data.

  • Wide range of services

CD Formulation focuses on R&D and testing services, and has accumulated many customers, including many well-known universities, laboratories, pharmaceutical companies, etc. Always customer-centric, constantly improve the comprehensive service capabilities, dedicated to serving the global field of research and analysis, testing platform.

If you have a requirement about our services, please contact us by phone or email, our colleagues will reply to you within three working days.

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Please note: Our products and services are not intended to be used directly in diagnostic or therapeutic procedures.
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