Lotions generally refers to the liquid preparation for skin or cavity daubing or cleaning, which is extracted by appropriate methods. Water and ethanol are usually used as dispersing media. There may be separation of oil phase and water phase when emulsion lotion is stored, but it should be easily redistributed after shaking: the sediment after suspension lotion is placed should be easy to disperse and have enough stability after shaking; the lotion that is easy to deteriorate should be configured before use. Generally, lotion has the functions of cleaning, disinfection, antipruritic, astringency and protection. Commonly used benzyl benzoate lotion, calamine menthol lotion, etc.
Fig.1 Calamine lotion is used to treat itching(wikipedia).
The team of CD Formulation is leading experts in all aspects of pharmaceutical formulation development and dosage form optimization, we can accord the characteristics of the API and the development goals of the customers to design the formulation of lotions. CD Formulation can provide you with one-stop services to meet your needs of lotions.
The Process of Developing Lotions
The lotion can be prepared in the following ways:
(1) Grind the ingredients into a smooth paste, then carefully add the remaining liquid phase or large amount using a high-speed mixer or homogenizer. The classic example is the Calamine emulsion, consisting of fine powdered insoluble solids and retained in more or less permanent suspensions due to the presence of suspending agents and / or surfactants.
(2) Through chemical interactions in liquids. For example: the second lotion approved by USP XVII is a surfactant stabilized O/W type.
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