Polymeric nanospheres consist of dense polymeric matrices such as chitosan, poly(lactic-co-glycolic acid) ( PLGA), poly(lactic acid) ( PLA) and poly(butyl cyanoacrylate) ( PBCA), which are widely used in the diagnosis and treatment of diseases. Active drug ingredients, either small molecules or biological compounds, can be encapsulated into nanospheres or attached to the particle surface for specific drug delivery applications, such as sustained release, targeted drug delivery, and API protection against premature degradation. The ionic cross-linking method is one of the basic methods for making nanospheres and is applicable to nanospheres made of chitosan, sodium alginate, etc. The main principle is that the material used as a drug carrier is precipitated from the emulsion by ionic cross-linking method, while the drug is encapsulated in the carrier by hydrogen bonding interactions and hydrophobic interactions, thus preparing into drug-carrying nanospheres.
CD Formulation can provide customization services for polymeric nanospheres. We verify the compatibility of drug carriers and drug systems before the nanospheres are used in drug delivery studies and pharmaceuticals, or for loading drug molecules into carriers. We help our customers to better develop and transport drugs efficiently.
Polymer nanosphere particles can be modified by surface groups to allow covalent attachment of proteins, peptides, and small molecules, facilitating the targeting of this drug delivery system and increasing the cycle time. Also, we can modify the polymer components to modulate the drug release properties of polymeric nanospheres.
Nanospheres have extremely strong adsorption properties due to their huge specific surface area, which allows them to selectively adsorb drugs through surface functional group modifications. Nanospheres as drug carriers have the advantages of improving drug utilization and selectivity, reducing the harm of drugs to normal tissues, reducing toxic side effects, and targeting drug delivery to lesions to achieve targeted drug delivery.
We have a personalized screening program and customization system, which also includes tracking services.
We have cutting-edge drug transport technology, polymer modification technology, etc., and also cover all kinds of testing instruments and equipment to ensure the smooth conduct of experiments.
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Our company has a team of top-notch technical and experienced experts who will provide authoritative solutions for your projects on a one-to-one basis.
CD Formulation provides integrated innovation solutions from strategy to implementation to help you increase opportunities and address challenges. Through our in-depth experience in many different industries, including consumer and technology, we bring innovative solutions and cross-industry best practices to drug development. If you have a requirement about our services, please contact us by phone or email, our colleagues will reply to you within three working days.
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