Preservatives can inhibit the growth of microorganisms and ensure the safety and effectiveness of cosmetics during production, use and preservation. CD Formulation can provide preservative content testing services to help customers quickly understand sample performance and better conduct follow-up research.
In the process of production and use of cosmetics, it is inevitable that there will be microbial invasion. If you do not add effective ingredients to inhibit microorganisms, it may deteriorate, not reach the desired effect, and even threaten the health of the user. Preservative is a substance added to cosmetics for the purpose of inhibiting microorganisms in cosmetics.
At present, there are high performance liquid chromatography, gas chromatography and gas chromatography-mass spectrometry for the determination of preservatives in cosmetics. High performance liquid chromatography (HPLC) is the most widely used preservative analysis method at present. Because most of the preservatives are macromolecular organic compounds, and have UV absorption characteristics, it is more suitable for HPLC analysis. This method has the advantages of simple operation and high sensitivity.
CD Formulation provides these detectors, which can test the sample efficiently and quickly, helping customers get the content of preservatives in cosmetics. The detailed procedure is as follows.
|Permissible preservatives for cosmetics|
|No.||Name of preservatives||No.||Name of preservatives|
|1||Bronopol (INN)||25||1,6-Di(4-amidinophenoxy)-n-hexane and its salts (including isethionate and p-hydroxybenzoate)|
|3||5-Ethyl-3,7-dioxa-1- azabicyclo[3.3.0]octane||27||3,3'-Bis(1-hydroxymethyl-2,5- dioxoimidazolidin-4-yl)-1,1'- methylenediurea|
|4||Alkyl(C12-C22) trimethyl ammonium bromide and chloride||28||Inorganic sulfites and hydrogensulfites|
|5||Benzalkonium chloride, bromide and saccharinate||29||3-Iodo-2-propynylbutylcarbamate|
|7||Benzoic acid, its salts and esters||31||Mixture of 5-chloro-2- methylisothiazol-3(2H) -one and 2- methylisothiazol-3(2H)-one with magnesium chloride and magnesium nitrate (of a mixture in the ratio 3:1 of 5-chloro- 2- methylisothiazol 3(2H)-one and 2-methylisothiazol-3 (2H)-one)|
|9||Benzylhemiformal||33||Biphenyl-2-ol and its salts|
|10||6,6-Dibromo-4,4-dichloro-2,2'- methylene-diphenol||34||4-Hydroxybenzoic acid and its salts and esters|
|11||Chlorhexidine (INN) and its digluconate,diacetate and dihydrochloride||35||4-Chloro-m-cresol|
|14||3-(p-chlorophenoxy)-propane-1,2- diol||38||1-Hydroxy-4-methyl-6(2,4,4- trimethylpentyl)2-pyridon and its monoethanolamine salt|
|15||1-(4-chlorophenoxy)-1-(imidazol-1- yl)-3,3-dimethylbutan-2-one||39||Poly(methylene),.alpha.,.omega.-bis[[[(aminoiminomethyl)amino]iminomethyl]amino]-, dihydrochloride|
|16||3-Acetyl-6-methylpyran-2,4 (3H)- dione and its salts||40||Propionic acid and its salts|
|17||N-(Hydroxymethyl)-N-(dihydroxymethyl-1,3-dioxo-2,5-imidazolinidyl-4)-N'- (hydroxymethyl) urea||41||Salicylic acid and its salts|
|18||3,3'-Dibromo-4,4'- hexamethylenedioxydibenzamidine and its salts (including isethionate)||42||Silver chloride deposited on titanium dioxide|
|19||2,4-Dichlorobenzyl alcohol||43||Sodium hydroxymethylamino acetate|
|20||4,4-Dimethyl-1,3-oxazolidine||44||Sorbic acid (hexa-2,4-dienoic acid) and its salts|
|21||1,3-Bis(hydroxymethyl)-5,5- dimethylimidazolidine-2,4-dione||45||Triclocarban (INN)|
|22||Ethyl-N-alpha- dodecanoyl-Larginate hydrochloride||46||Triclosan (INN)|
|23||Formic acid and its sodium salt||47||Undec-10-enoic acid and its salts|
|24||Glutaraldehyde (Pentane-1,5-dial)||48||Pyrithione zinc (INN)|
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