Nasal Sprays Formulation Development

Nasal spray is used to deliver drugs locally or systemically in the nasal cavity. They are used locally for diseases such as nasal congestion and allergic rhinitis. In some cases, nasal route is more suitable for systemic therapy because it provides a good choice for injection or pill. Drugs can be absorbed very quickly and directly through the nose, many drugs exist in the form of nasal spray for systemic administration (for example, pain, migraine, osteoporosis and nausea), and other applications of nasal spray include hormone replacement therapy, Alzheimer's disease and Parkinson's disease. So nasal spray is considered a more effective way of drug delivery and can be used to cross the blood-brain barrier.

Nasal SpraysFig.1 Spray into nostril.

The team of CD Formulation is leading experts in all aspects of pharmaceutical formulation development and dosage form optimization, we can accord the characteristics of the API and the development goals of the customers to design the formulation of nasal sprays. CD Formulation can provide you with one-stop services to meet your needs of nasal sprays.

Advantages of Nasal Sprays

  • Compared to oral administration, absorption in the nose can be rapid.
  • Greater bioavailability can be achieved.
  • As long acting forms of drug injected intramuscularly or implanted into the body.
  • Absorption into the blood happens without first undergoing enzymatic degradation in the gastrointestinal (GI) tract nor first pass metabolism in the liver, faster onset, and at a lower dose.
  • Systemically acting drugs could be more effective and safer when delivered intranasally directly to the blood supply within the turbinates.

Our Services

  • Dosage form development
  • Formulation selection and optimization
  • Product testing
  • In-vitro bioequivalence testing
  • Release and finished product testing
  • Particle sizing, droplet sizing and spray analysis
  • Drug and delivery assays
  • Stability studies
  • Structural elucidation of drug-related impurities and degradation products
  • Extractables and leachables studies
Nasal Sprays
How to Contact Us?

If you have a requirement about nasal sprays services, please contact us by phone or email, our colleagues will reply to you within three working days.


  1. Jason D, Samir A, Charles S, et al. Considerations for the Development of Nasal Dosage Forms[J]. AAPS Advances in the Pharmaceutical Sciences Series, 2013, 6: 99-144.
  2. Santosh T. Formulation and Product Development of Nasal Spray: An Overview[J]. Scholars Journal of Applied Medical Sciences, 2016; 4(8D): 2976-2985.
  3. Christian, A. Nasal Spray to the Rescue of Neurons in Stroke[J]. Molecular Therapy the Journal of the American Society of Gene Therapy, 2018, 26(10): 2333-2334.
Online Inquiry
Please note: Our products and services are not intended to be used directly in diagnostic or therapeutic procedures.
Enter your email here to subscribe.

Easy access to products and services you need from our library via powerful searching tools.

Copyright © CD Formulation. All Rights Reserved.  Privacy Policy | Cookie Policy