Tablet Hardness Test

Solid tablets are probably the most commonly used dosage form of drugs. Tablet hardness can be used not only as a standard to guide product development, but also as a quality control indicator. Tablets should not be too hard or too soft. Extremely hard tablets may indicate that the binding force between the active ingredient and the excipient is too great, which may prevent the proper dissolution of the tablet needed for an accurate dosage. Similarly, softer tablets may be the result of weak binding and may cause premature disintegration when ingested by patients.

Tablet Hardness Test

CD Formulation can provide analytical services for a variety of dosage forms. Our laboratory is cGMP-compliant and equipped with state of the art analytical instruments. Our scientists conduct proven analytical process development and validation services and work as an integrated team to provide solutions that make your project a success. At CD Formulation , all tablet hardness test meet the latest requirements of Pharmacopeia.

Factors That Could Affect the Hardness of Tablets

  • The speed of compression
  • The flow and air entrapment
  • Formulation variable
  • Process parameters

Methods of Tablet Hardness Test

Tablet Hardness Test Crush test on tablet

Tablet Hardness Test Fracture test on tablet

Tablet Hardness Test A blade splits the tablet in a bending test

Deliverable

  • Data analysis
  • Provide full study report

Our Advantages

Tablet Hardness Test Services

How to Contact Us?

If you have a requirement about tablet hardness test services, please contact us by phone or email, our colleagues will reply to you within three working days.

References

  1. Seitz, James A., and Gerald M. Flessland. "Evaluation of the Physical Properties of Compressed Tablets I. Tablet Hardness and Friability." Journal of Pharmaceutical Sciences 54.9 (1965): 1353-1357.
  2. Herrmann, Konrad, ed. Hardness Testing: Principles and Applications. ASM international, 2011.

Online Inquiry

Please note: Our products and services can only be used for research purposes. Do not use in diagnostic or therapeutic procedures!
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