Sublingual Tablets

Sublingual tablets are those tablets that are placed beneath the tongue where they can dissolve or disintegrate quickly and are absorbed directly without passing into GIT (gastro intestinal tract). When the rapid onset of action is required rather than oral, the sublingual route is a preferable route, due to sublingual tablets can quickly release the drug from the preparation and reach systemic direct circulation, bypassing drug metabolism in the liver and enhanced bioavailability.

Fig.1 Image of drug tablet being placed underneath the tongue to enable sublingual to dissolve and delivery. (Nandini, 2011)

The team of CD Formulation is leading experts in all aspects of pharmaceutical formulation development and dosage form optimization, we can accord the characteristics of the API and the development goals of the customers to design the formulation of sublingual tablets. CD Formulation can provide you with one-stop services to meet your needs of sublingual tablets.

Technologies Used for Sublingual Tablets

• Direct compression
• Freeze drying/ lyophilisation
• Molding
• Sublimation
• Cotton candy process
• Spray drying
• Mass extrusion
• Melt granulation

The Process of Developing Sublingual Tablets

The usage of sublingual tablets are different from that of common oral tablets, so the preparation method of sublingual tablets are different from that of common tablets.

How to Contact with Us?

If you have a requirement about sublingual tablets services, please contact us by phone or email, our colleagues will reply to you within three working days.

References

1. Prathusha P, Praneeth Kamarapu. A Review on Sublingual Tablets [J]. Journal of Formulation Science & Bioavailability, 2017.
2. Katz M, Barr M. A Study of Sublingual Absorption. I. Several Factors Influencing the Rate of Absorption[J]. Journal of the American Pharmaceutical Association, 1955, 44(7): 419-423.
3. Khan A B, Kingsley T, Caroline P. Sublingual Tablets and the Benefits of the Sublingual Route of Administration[J]. Journal of Pharmaceutical Research, 2017, 16(3): 257-267.