Sunscreens and sun sprays are important sun protection. However, some may contain substances that are suspected to be endocrine disrupting or harmful to the environment. Chemical-based sunscreens use organic compounds to filter UV rays. They are absorbed into the skin and provide sun protection by absorbing UV rays, either releasing the energy from the light as heat or changing the 3D shape of the chemical, which then breaks down.
Common chemical sunscreen ingredients include Benzophenone (C13H10O), Ethylhexyl salicylate (C15H20O3), Homosalate (C16H22O3), Cinoxate (C14H18O4), Phenyl Dibenzimidazole Tetraxanthate Disodium (C20H12N4Na2O12S4), Butyl Methoxydibenzoylmethane (C20H22O3), Ethylhexyl Methoxycinnamate (C18H26O3) and Mexoryl, etc.
The efficacy of sunscreen products mainly depends on its SPF and PFA values. These two parameters represent the wavelengths that sunscreen products can protect against:
SPF=UVA+UVB, wavelength 280-400 nm.
PFA=UVA, wavelength 320-400 nm.
Subjects were placed in a prone position, and their backs were irradiated. The minimum erythema (MED value) of the subject's skin to ultraviolet radiation was predicted 24 hours before the test, and the ultraviolet radiation dose was adjusted according to the predicted results for the test sample. On the day of the test, first select a 7 cm ×7 cm normal skin area on the back of the subject, apply the sample to be tested or the standard control substance evenly on the above-mentioned area according to the sample dosage of (2.00±0.05) mg/cm, and then select the appropriate ultraviolet radiation dose.
Irradiation was carried out in three situations:
CD Formulation has been conducting cosmetic inspection work for a long time, including patch test, human trial test, sunscreen cosmetics sun protection index test, etc. At the same time, according to the requirements of cosmetics companies, we can conduct research on the safety of cosmetics on the human body and the efficacy of cosmetic sensory evaluations such as freckle removal, moisturizing, whitening, acne removal, oil control, dandruff removal, and hair.
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