Thermal analysis, refers to the process of measuring the physicochemical properties of a substance as a function of temperature under programmed temperature control and determining whether the crystalline forms of drugs are different from each other from the measured thermal analysis curves. However, since drugs have different crystalline forms, they may also absorb and exert heat differently when heated or cooled. CD Formulation tests samples by differential scanning calorimetry, differential thermal analysis and thermogravimetric analysis to gain more insight into the morphological characteristics and degradation pathways of the crystalline ground, thus facilitating the development and commercialization of the drug product.
Fig.1 DSC and TGA curves of R-RW (Tong, 2005)
CD Formulation has the scientific and analytical expertise to help our customers characterize their samples and guide their drug development. CD Formulation can analyze the crystalline morphology of drug crystals by collecting data from differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and differential thermal analysis.
CD Formulation can provide thermal analysis services for a wide range of drugs in our compliant laboratory, which is equipped with state-of-the-art analytical instrumentation. Our scientists provide proven analytical process development and validation services, and work as an integrated team to provide solutions that will make your project a success.
If you have a requirement about our services, please contact us by phone or email, our colleagues will reply to you within three working days.