Ointment base is a drug excipient used as a carrier or vehicle for the active ingredient in topical formulations. It is the main component of the formulation and provides the physical structure, consistency and texture of the final product.
These are ointment bases that contain a mixture of water and oil; they are usually more readily absorbed into the skin and are less greasy than hydrocarbon bases.
These are ointment bases that consist of a mixture of oil and water, along with an emulsifier to help keep these two phases together.
These ointment bases consist of a mixture of water-soluble polymers. They are usually non-greasy and wash off easily with water.
Ointment matrices play a key role in determining the effectiveness, stability and usability of the final product and can have a significant impact on patient outcomes. The following factors currently need to be considered when examining the ointment base.
The ability of active ingredients to penetrate the skin can be influenced by the type of ointment base used. Water soluble bases may provide better penetration due to their ability to moisturize the skin.
The choice of ointment base can affect the stability of the active ingredient. For example, certain active ingredients may degrade or become less effective in certain types of ointment matrices.
The choice of ointment matrix can also affect patient compliance and satisfaction.
The desired texture, consistency and appearance of the final product may also influence the choice of ointment base. The choice of ointment base should be carefully considered in light of the specific needs of the formulation and the intended use of the end product.