CD Formulation has professional production facilities and management experience, as well as professional staff with extensive expertise. We can provide coating systems excipients with different specifications and quality requirements, and customize the production of corresponding products according to customer needs.
Medical coating is a technique for applying the outer dry film of the coating composition to the required dosage forms (mainly tablets and granules) to obtain specific advantages (masking mouthfeel, environmental protection). We offer coating systems excipients, which add coatings to tablets to help make large pills that are difficult to swallow easier to take. They can also prevent deterioration due to water and humidity. The coating can also cause the breakdown of certain organs of the body. For example, enteric coating allows decomposition in the small intestine and prevents decomposition in the acidic environment of the stomach. For many coated tablets, the cellulose ether hydroxypropyl methyl cellulose (HPMC) film coating, which does not contain sugar and potential allergens, is used. Other coating materials are also used, such as synthetic polymers, shellac, zein or other polysaccharides.
Many pharmaceutical products, including pills, granules, capsules, powders, and crystals, usually require coatings. The process of coating the tablets is a complicated process that causes a thin layer to form around the tablets. The thickness of this layer is in the range of 20 to 200 μm, or about 1% to 9% of the initial weight of the tablet.
According to the solubility of functional coating excipients, it can be divided into three types: gastric-soluble type, enteric-soluble type and insoluble type. Different types of functional coating auxiliary materials have different permeability, mechanical stability, solubility, etc., and the two-by-two mixing can achieve the ideal effect that a single type of coating auxiliary material cannot achieve.
Hydroxypropyl methyl cellulose (HPMC) is a commonly used stomach soluble coating excipients, other stomach soluble coating polymer excipients and polyvinyl alcohol (PVA), hydroxypropyl cellulose (HPC), polyethylene glycol (PEG), polyethylene acetal diethyl adhesive acetate (AEA), acrylic resin in the E type.
Enteric coating excipients can be used alone or in combination with other excipients to prepare coating preparations, such as shellac, polyvinyl acetate benzoate (PVAP), algin, cellulose and acrylic resins.
If you have any requirements for coating systems excipients, please do not hesitate to contact us for more information or to discuss in detail, and our colleagues will reply to you within 2-4 working days.