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Products
Azacitidine
Product Details
Molecular Formula
C8H12N4O5
Molecular Weight
244.2
Appearance
lyophilized powder
Grade
Pharmaceutical grade
Standard
USP
Description
Azacitidine functions as a pyrimidine nucleoside analog that incorporates into DNA and RNA. Its primary action is inhibition of DNA methyltransferase, leading to global DNA hypomethylation and subsequent reactivation of silenced tumor suppressor genes. This promotes differentiation and apoptosis of abnormal hematopoietic cells.
CAS Number
320-67-2
Stability and Storage Conditions
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Solubility
Soluble in DMSO (up to 25 mg/ml), or in Water (up to 12 mg/ml).
Storage
-20°C
Boiling Point
387.12°C (rough estimate)
Melting Point
226-232 °C (dec.)(lit.)
Density
1.4287 (rough estimate)
Applications
Azacitidine is a hypomethylating antineoplastic agent primarily used in the treatment of hematologic malignancies.
EC Number
206-280-2
Color
White to Off-white
MDL number
MFCD00006539
Water Solubility
0.5-1.0 g/100 mL at 21 ºC
InChI Key
NMUSYJAQQFHJEW-WGDKFINWSA-N
WGK Germany
3
RTECS
XZ3017500
LogP
-2.191 (est)
F
10-23
Online Inquiry
Please note: Our products and services are not intended to be used directly in diagnostic or therapeutic procedures.
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