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Calcium Stearate
Product Details
Category
Tablet and Capsule Lubricant; Emulsifiers; Stabilizers; Suspending Agentss
Molecular Formula
C36H70CaO4
Molecular Weight
607.03 (for pure material)
Grade
Pharmceutical Excipients
Description
Calcium stearate occurs as a fine, white to yellowish-white, bulky powder having a slight, characteristic odor. It is unctuous and free from grittiness.
UNII
776XM7047L
Chemical Name
Octadecanoic acid calcium salt
CAS Number
1592-23-0
Synonyms
Calcii stearas; calcium distearate; calcium octadecanoate; Deasit PC; HyQual; Kemistab EC-F; octadecanoic acid, calcium salt; stearic acid, calcium salt; Synpro
Administration route
Oral
Dosage Form
Oral capsules and tablets
Stability and Storage Conditions
Calcium stearate is stable and should be stored in a well-closed container in a cool, dry place.
Source and Preparation
Calcium stearate is prepared by the reaction of calcium chloride with a mixture of the sodium salts of stearic and palmitic acids. The calcium stearate formed is collected and washed with water to remove any sodium chloride.
Applications
Calcium stearate is primarily used in pharmaceutical formulations as a lubricant in tablet and capsule manufacture at concentrations up to 1.0% w/w. Although it has good antiadherent and lubricant properties, calcium stearate has poor glidant properties. Calcium stearate is also employed as an emulsifier, stabilizing agent, and suspending agent, and is also used in cosmetics and food products.
Safety
Calcium stearate is used in oral pharmaceutical formulations and is generally regarded as a relatively nontoxic and nonirritant material.
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Please note: Our products and services are not intended to be used directly in diagnostic or therapeutic procedures.
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