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Docetaxel
Product Details
Molecular Formula
C43H53NO14
Molecular Weight
807.88
Appearance
Solid powder
Grade
Pharmaceutical grade
Standard
USP
Description
Docetaxel is a semi-synthetic taxane chemotherapeutic agent primarily used in oncology. It functions as a microtubule-stabilizing agent, binding to and stabilizing β-tubulin subunits to inhibit microtubule depolymerization. This disrupts mitotic spindle dynamics, arrests cells in the G2/M phase, and induces apoptosis.
CAS Number
114977-28-5
Stability and Storage Conditions
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Solubility
Practically insoluble in water, freely soluble in anhydrous ethanol, soluble in methylene chloride.
Storage
Sealed in dry,Store in freezer, under -20°C
Boiling Point
900.5±65.0 °C(Predicted)
Melting Point
186-192 °C (dec.)
Density
1.38
Applications
Docetaxel is a cornerstone chemotherapeutic agent with established applications in treating a range of solid tumors. Its primary clinical uses include treatment of advanced or metastatic non-small cell lung cancer, management of metastatic castration-resistant prostate cancer., et.
EC Number
601-339-2
Color
White
MDL number
MFCD00871399
pH
1.20±0.46(Predicted)
InChI Key
BEDLLNJKXXVTSX-LWWLJZAUSA-N
WGK Germany
3
RTECS
DA4172750
LogP
2.456 (est)
Online Inquiry
Please note: Our products and services are not intended to be used directly in diagnostic or therapeutic procedures.
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