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Ibandronate sodium
Product Details
Molecular Formula
C9H24NNaO7P2
Molecular Weight
343.23
Appearance
Solid
Grade
Pharmaceutical grade
Standard
USP
Description
Ibandronate sodium is the sodium salt form of ibandronic acid, serving as the active pharmaceutical ingredient (API) in the nitrogen-containing bisphosphonate class. It functions as a potent inhibitor of osteoclast-mediated bone resorption by selectively binding to hydroxyapatite crystals in bone tissue, disrupting the mevalonate pathway within osteoclasts, and ultimately inducing osteoclast apoptosis, thereby significantly reducing bone turnover.
CAS Number
138844-81-2
Stability and Storage Conditions
Hygroscopic
Solubility
H2O: >10mg/mL
Storage
2-8°C
Applications
The Ibandronate sodium is primarily used in the manufacture of oral tablets and injectable solutions for the treatment and prevention of osteoporosis in postmenopausal women. Its applications include increasing bone mineral density, reducing the risk of vertebral fractures, and, in its intravenous formulation, managing metastatic bone disease in patients with breast cancer to reduce skeletal-related events such as pathological fractures and spinal cord compression.
Color
White
MDL number
MFCD07197214
SMILES
C(O)(P(O)(O)=O)(P(O)(O)=O)CCN(C)CCCCC.[NaH]
InChI
InChI=1S/C9H23NO7P2.Na.H/c1-3-4-5-7-10(2)8-6-9(11,18(12,13)14)19(15,16)17;;/h11H,3-8H2,1-2H3,(H2,12,13,14)(H2,15,16,17);
Water Solubility
H2O: >10mg/mL
InChI Key
LXLBEOAZMZAZND-UHFFFAOYSA-M
WGK Germany
3
RTECS
SZ8563300
Online Inquiry
Please note: Our products and services are not intended to be used directly in diagnostic or therapeutic procedures.
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