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L-Histidine hydrochloride
Product Details
Molecular Formula
C6H10ClN3O2
Molecular Weight
191.62
Appearance
White to off-white Solid
Grade
Pharmaceutical grade
Standard
EP/JP
Description
Histidine Hydrochloride (specifically L-Histidine Hydrochloride Monohydrate, C₆H₉N₃O₂·HCl·H₂O) is the hydrochloride salt of the essential amino acid L-histidine. It exists as a white, crystalline, odorless powder with a characteristic sour taste. Its distinctive chemical feature is the imidazole side chain, which gives it unique acid-base and metal-chelating properties, making it versatile in pharmaceutical formulations.
CAS Number
1007-42-7
Stability and Storage Conditions
Stable.
Storage
Inert atmosphere,Room Temperature
Melting Point
240-245 °C (dec.)
Applications
As an active pharmaceutical ingredient (API) in nutrition and therapy, it is used in the management of histidinemia (a rare metabolic disorder) and as a potential adjunct in conditions like rheumatoid arthritis (due to its role in histamine metabolism, though evidence is limited).
Product Description
Histidine Hydrochloride plays a dual and critical role in modern medicine. As an active nutrient, it is essential in clinical nutrition. More importantly, as a highly functional excipient, it is indispensable for stabilizing and protecting the integrity of advanced biologic therapeutics, particularly monoclonal antibodies.
EC Number
213-754-2
Color
White to off-white
MDL number
MFCD00066569
SMILES
C(C1N=CNC=1)[C@H](N)C(=O)O.Cl |&1:6,r|
InChI
InChI=1/C6H9N3O2.ClH/c7-5(6(10)11)1-4-2-8-3-9-4;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H/t5-;/s3
InChI Key
QZNNVYOVQUKYSC-USHJBNIQNA-N
WGK Germany
3
F
3-10
Online Inquiry
Please note: Our products and services are not intended to be used directly in diagnostic or therapeutic procedures.
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