Product Details
Molecular Formula
C172H265N43O51
Molecular Weight
3751.202
Appearance
White to off-white powder; the injectable solution is clear and colorless
Grade
Pharmaceutical grade
Standard
In-house standard
Description
An acylated analogue of human glucagon-like peptide-1 (GLP-1)
Stability and Storage Conditions
Stable as a solid; has an extended half-life in plasma (~13h) due to fatty acid side chain.
Solubility
Freely soluble in aqueous base solutions (>270 mg/mL); solubility decreases below pH 7. Soluble in DMSO and water
Storage
Store in a refrigerator
Melting Point
>182°C (dec.)
Applications
A GLP-1 receptor agonist used as a subcutaneous injection for the treatment of type 2 diabetes (Victoza) and chronic obesity (Saxenda)
InChI Key
YSDQQAXHVYUZIW-VTFFJMQZNA-N