Product Details
Molecular Formula
C20H22N5NaO6
Appearance
Off-White solid powder
Grade
Pharmaceutical grade
Description
Pemetrexed Disodium works by inhibiting multiple folate-dependent enzymes (thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleotide formyltransferase) essential for DNA and RNA synthesis, thereby disrupting cancer cell proliferation.
Stability and Storage Conditions
Hygroscopic
Solubility
Soluble in methanol, water
Storage
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Melting Point
254-258°C (dec.)
Applications
Pemetrexed disodium is a cornerstone chemotherapy drug with a well-defined role in the management of specific, non-squamous thoracic malignancies.
SMILES
C(C1=CNC2NC(N)=NC(=O)C1=2)CC1C=CC(C(=O)N[C@H](C(=O)O)CCC(=O)O)=CC=1.[NaH] |&1:20,r|
InChI Key
UTEALKYVANXUSG-NVZXTOETNA-N