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Povidone K30
Product Details
Category
Binder; Solubilizer; Suspending Agents; Stabilizer; Viscosifier; Coating material
Molecular Formula
(C6H9NO)n
Molecular Weight
50000
Grade
Pharmceutical Excipients
Description
Povidone darkens to some extent on heating at 150℃, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-136℃; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives.Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place.
UNII
U725QWY32X
Chemical Name
1-Ethenyl-2-pyrrolidinone homopolymer
CAS Number
9003-39-8
Synonyms
Poly[1-(2-oxo-1-pyrrolidinyl)ethylene]; polyvinylpyrrolidone; povidonum; Povipharm; PVP; 1-vinyl-2-pyrrolidinone polymer
Administration route
Oral, sublingual, ocular
Dosage Form
IM and IV injections; ophthalmic preparations; oral capsules, drops, granules, suspensions, and tablets; sublingual tablets; topical and vaginal preparations
Stability and Storage Conditions
Povidone darkens to some extent on heating at 150℃, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-131℃; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives. Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place.
Commonly used amount and the maximum amount
Povidone darkens to some extent on heating at 150℃, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-135℃; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives. Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place.
Source and Preparation
Povidone darkens to some extent on heating at 150℃, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-136℃; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives. Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place.
Applications
Povidone darkens to some extent on heating at 150℃, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-134℃; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives. Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place.
Safety
Povidone darkens to some extent on heating at 150℃, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-132℃; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives. Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place.
Incompatibilities
Povidone darkens to some extent on heating at 150℃, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-133℃; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives. Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place.
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Please note: Our products and services are not intended to be used directly in diagnostic or therapeutic procedures.
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