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Salcaprozate Sodium
Product Details
Molecular Formula
C15H22NNaO4
Molecular Weight
303.33
Appearance
White to Off-White
Grade
Pharmaceutical grade
Description
8-(2-Hydroxybenzamido)octanoic acid sodium salt, abbreviated as SNAC, is an absorption enhancer for dicarbonyl phosphate compounds. It is used in the treatment of gastrointestinal diseases, particularly those caused by malabsorption of dicarbonyl phosphate compounds in the gastrointestinal tract.
CAS Number
203787-91-1
Stability and Storage Conditions
Hygroscopic
Solubility
DMSO (Slightly), Methanol (Slightly)
Storage
Inert atmosphere,Room Temperature
Melting Point
183 - 185°C
Applications
Salcaprozate Sodium is a critical and innovative absorption enhancer that has revolutionized the field of oral formulations. Its primary application lies in facilitating the gastrointestinal absorption of large, hydrophilic molecules, such as peptides, that would otherwise be poorly bioavailable when taken orally. It achieves this through a transient and localized mechanism, primarily by chelating calcium ions to temporarily loosen epithelial tight junctions and by acting as a buffer to protect drugs from gastric acid.
Product Description
Salcaprozate Sodium (also known historically as SNAC) is a synthetic, non-toxic, medium-chain fatty acid derivative that functions as an absorption enhancer or permeation enhancer. Its primary and most notable action is to significantly improve the oral bioavailability of pharmaceutical drugs that would otherwise be poorly absorbed from the gastrointestinal (GI) tract.
EC Number
231-019-4
Molecular Weight (g/mol)
303.33
Color
White to Off-White
MDL number
MFCD00952954
SMILES
InChI=1S/C15H21NO4.Na.H/c17-13-9-6-5-8-12(13)15(20)16-11-7-3-1-2-4-10-14(18)19;;/h5-6,8-9,17H,1-4,7,10-11H2,(H,16,20)(H,18,19)
InChI
OBKUJEVXEMKQMJ-UHFFFAOYSA-N
InChI Key
OBKUJEVXEMKQMJ-UHFFFAOYSA-N
Online Inquiry
Please note: Our products and services are not intended to be used directly in diagnostic or therapeutic procedures.
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