Product Details
Molecular Formula
C24H41NaO4
Grade
Pharmaceutical grade
Description
Sodium deoxycholate is the sodium salt form of deoxycholic acid, a secondary bile acid naturally produced by intestinal bacteria, which serves as an active pharmaceutical ingredient (API) and a biochemical excipient. It functions primarily as a biological detergent due to its amphipathic structure, capable of solubilizing lipids and disrupting cell membranes by emulsifying fats and denaturing membrane proteins.
Stability and Storage Conditions
Stabiliy
Solubility
Water: soluble1 gm in 10 ml, clear, colorless to very faintly yellow
Applications
The Sodium deoxycholate API is utilized in pharmaceutical formulations as a solubilizing agent, absorption enhancer, and permeation promoter for poorly soluble drugs, particularly in injectable and topical products. Its clinical application includes its use as the active ingredient in injectable solutions for the non-surgical reduction of localized subcutaneous fat (e.g., treatment of submental fat), where it disrupts adipocyte membranes, leading to cell lysis and subsequent fat absorption and removal.
SMILES
[C@@H]1(OC(CC)CC)C=C(C[C@H](N)[C@H]1NC(=O)C)C(=O)OCC.OP(O)(O)=O |&1:0,10,12,r|
InChI
InChI=1/C16H28N2O4.H3O4P/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19;1-5(2,3)4/h9,12-15H,5-8,17H2,1-4H3,(H,18,19);(H3,1,2,3,4)/t13-,14+,15+;/s3
InChI Key
PGZUMBJQJWIWGJ-IFAKAUOZSA-N