Tragacanth

Category

Emulsifier; Suspending Agents; Gelling Agents; Slip Agents; Film forming Agents, etc

Grade

Pharmceutical Excipients

UNII

2944357O2O

Chemical Name

/

CAS Number

9000-65-1

Synonyms

E413; goat’s thorn; gum benjamin; gum dragon; gum tragacanth; persian tragacanth; trag; tragant; tragacantha

Administration route

Oral cavity; Oral administration; Sublingual; Topical

Dosage Form

Tablet, gelling agent, coating preparations

Stability and Storage Conditions

Store in a cool, dry place in an airtight container.

Source and Preparation

Astragalus gummifer Labill, a Leguminosae plant, is obtained by drying and extracting the gum that exudes from cut branches. This product is mainly composed of galactoarabinans and acid polysaccharides containing galacturonic acid groups.

Safety

This product is a natural polysaccharide, non-toxic.

Incompatibilities

At pH=7, Millefolium millefolium could significantly reduce the antibacterial and preservative effects of antiseptic preservatives benzalkonium chloride, chlorobutanol, hydroxyphenylate, and phenol and phenylmercuric acetate. However, at pH less than 5, Millefolium millefolium had no adverse effect on the preservative properties of benzoic acid, chlorobutanol or hydroxyphenylate. The viscosity of yarrow pulp was decreased by adding strong inorganic and organic acids. The viscosity of A.millefolium was also reduced by adding alkali, especially sodium chloride when heated. Yarrow gum has compatibility with high salt content and most natural or synthetic suspension AIDS such as acacia, carboxymethyl cellulose, starch and sucrose. The reaction of achillea millefolium with 10%(W/V) ferric chloride solution can form a filamentous yellow precipitate.